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Methods:

By way of flyers published in “rave” venues in Amsterdam, the Netherlands, we recruited 15 slight MDMA customers, 23 heavy MDMA customers, sixteen ex-MDMA customers who had stopped the use of MDMA for extra than 1 year, and 15 controls who claimed by no means to have used MDMA.  We studied the outcomes of MDMA on mind serotonin neurons the use of 123iodine-2beta-carbomethoxy-3beta-(4-iodophenyl) tropane beta-CIT)-a radioligand that binds with excessive affinity to serotonin transporters.  Density of binding (expressed as a ratio of region-of-hobby binding over binding with inside the cerebellum) changed into calculated through single-photon-emission computed tomography (SPECT).

EFFECTS

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• When you had your maximum current meal
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Substance: 3,4-mеthуlеnеdіоxу-N-mеthуlаmрhеtаmіnе
Dоѕаgе: mаx. 1.5 mg MDMA реr kg body wеіght fоr mеn, mаx. 1.3 mg per kg
Bоdуwеіght for wоmеn.
Onѕеt/durаtіоn оf action: after approx. 30 minutes / 4-6 hours